Methionine Sulfoxide

Methionine Sulfoxide

SCHEMBL689512

C[S@+]([O-])CC[C@H](N)C(=O)O

nearest known ligand 0.47

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 2/20 0.46
GRM8 O00222 1/20 0.46
GRM6 O15303 1/20 0.46
GRIN2D O15399 1/20 0.46
GRIN3B O60391 1/20 0.46
CYP1A2 P05177 1/20 0.46
GRIK1 P39086 1/20 0.46
GRM5 P41594 1/20 0.46
GRIA1 P42261 1/20 0.46
GRIA2 P42262 1/20 0.46
GRIA3 P42263 1/20 0.46
SLC1A3 P43003 1/20 0.46
SLC1A2 P43004 1/20 0.46
SLC1A1 P43005 1/20 0.46
GRIA4 P48058 1/20 0.46
GRIN1 Q05586 1/20 0.46
GRIN2A Q12879 1/20 0.46
GRIK2 Q13002 1/20 0.46
GRIK3 Q13003 1/20 0.46
GRIN2B Q13224 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methionine Sulfoxide SCHEMBL38627 1.00 GSR (0.46) GSRGRM8GRM6GRIN2DGRIN3B
Methionine Sulfoxide SCHEMBL14448373 1.00 GSR (0.46) GSRGRM8GRM6GRIN2DGRIN3B
Methionine Sulfoxide SCHEMBL995666 1.00 GSR (0.46) GSRGRM8GRM6GRIN2DGRIN3B
Methionine Sulfoxide SCHEMBL288041 1.00 GSR (0.46) GSRGRM8GRM6GRIN2DGRIN3B
Methionine Sulfoxide SCHEMBL689456 1.00 GSR (0.46) GSRGRM8GRM6GRIN2DGRIN3B
Methionine Sulfoxide SCHEMBL38626 1.00 GSR (0.46) GSRGRM8GRM6GRIN2DGRIN3B
Methionine Sulfoxide SCHEMBL4418369 1.00 GSR (0.46) GSRGRM8GRM6GRIN2DGRIN3B
Methionine Sulfoxide SCHEMBL22076611 0.98 GSR (0.45) GSRGRM8GRM6GRIN2DGRIN3B
Methionine Sulfoxide SCHEMBL28993578 0.96 GGT1 (0.44) GSRGRM8GRM6GRIN2DGRIN3B
Methionine Sulfoxide SCHEMBL16176754 0.94 GSR (0.42) GSRGRM8GRM6GRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190072565-A1 PROTEIN PREPARATION PIERCE BIOTECHNOLOGY, INC. 2019-03-07 US claimed
EP-3402894-A1 PROTEIN PREPARATION BY REDUCTION OF OXIDIZED METHIONINES Pierce Biotechnology, Inc. (US) 2018-11-21 EP claimed
WO-2017123440-A1 PROTEIN PREPARATION BY REDUCTION OF OXIDIZED METHIONINES PIERCE BIOTECHNOLOGY, INC. (US) 2017-07-20 WO claimed
EP-2629774-A2 CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES Elcelyx Therapeutics, Inc. (US) 2013-08-28 EP claimed
WO-2012054530-A2 CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES ELCELYX THERAPEUTICS, INC. (US) 2012-04-26 WO claimed
US-11753222-B2 Powdered pouch and method of making same MONOSOL, LLC (US) 2023-09-12 US disclosed
EP-2825624-B2 WATER SOLUBLE COMPOSITIONS INCORPORATING ENZYMES, AND METHOD OF MAKING SAME MONOSOL LLC (US) 2022-07-27 EP disclosed
EP-2838811-B2 POWDERED POUCH AND METHOD OF MAKING SAME MONOSOL LLC (US) 2022-06-29 EP disclosed
WO-2022103124-A1 FLUORESCENT PROTEIN SENSOR CAPABLE OF QUANTITATIVELY MEASURING FREE METHIONINE-R-SULFOXIDE, AND USE THEREOF 고려대학교 산학협력단 2022-05-19 WO disclosed
CN-111454917-B Methionine sulfoxide reductase and encoding gene, preparation method and application thereof 深圳大学 2022-05-17 CN disclosed
CN-109722459-B 5-aminolevulinic acid high-yield strain and preparation method and application thereof 中国科学院天津工业生物技术研究所 2021-12-24 CN disclosed
US-10781248-B2 α1-antitrypsin compositions and methods of treating autoimmune diseases BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) 2020-09-22 US disclosed
US-20070122491-A1 Methods and compositions for altering cell function ALLTECH, INC. (US) 2007-05-31 US disclosed
EP-1779857-A1 Use of selenium compounds, especially selenium yeasts in the treatment of Alzheimer, neurodegenerative diseases and diabetes Alltech, Inc. (US) 2007-05-02 EP disclosed
EP-1779856-A1 Use of selenium compounds, especially selenium yeasts in the treatment of Alzheimer, neurodegenerative diseases and diabetes Alltech, Inc. (US) 2007-05-02 EP disclosed
EP-1779858-A1 Use of selenium compounds, especially selenium yeasts for altering cognitive function Alltech, Inc. (US) 2007-05-02 EP disclosed
EP-1774972-A1 Use of selenium compounds, especially selenium yeasts in the treatment of Alzheimer, neurodegenerative diseases and diabetes Alltech, Inc. (US) 2007-04-18 EP disclosed
WO-2005086794-A2 LACTOBACILLUS ACIDOPHILUS NUCLEIC ACID SEQUENCES ENCODING STRESS-RELATED PROTEINS AND USES THEREFOR NORTH CAROLINA STATE UNIVERSITY (US) 2005-09-22 WO disclosed
EP-0576949-B1 Optically active amino acid sulphoxide and sulphone derivatives, their preparation, their polymerisation and use as adsorbents for chromatograpic separation of racemates BAYER AG (DE) 1996-01-31 EP disclosed
EP-0576949-A1 Optically active amino acid sulphoxide and sulphone derivatives, their preparation, their polymerisation and use as adsorbents for chromatograpic separation of racemates BAYER AG (DE) 1994-01-05 EP disclosed