Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 20/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3363815 | 0.89 | CRHR1 (0.42) | CRHR1 | |
| SCHEMBL3362573 | 0.82 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL3366885 | 0.80 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL3364646 | 0.79 | CRHR1 (0.49) | CRHR1 | |
| SCHEMBL8296189 | 0.78 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL3365289 | 0.78 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL3363779 | 0.78 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL3365427 | 0.76 | CRHR1 (0.60) | CRHR1 | |
| SCHEMBL3364041 | 0.76 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL3363721 | 0.76 | CRHR1 (0.50) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016892-A1 | GABANERGIC MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-02-24 | — | — | WO | disclosed |