Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCH | P24723 | 2/20 | 0.52 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.52 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CDC7 | O00311 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6382426 | 0.87 | IDO1 (0.54) | DHODHKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL9629001 | 0.82 | TRPM4 (0.48) | KDM4EALDH1A1MAPTHPGDCYP1A2 | |
| SCHEMBL2155064 | 0.81 | CYP11B1 (0.61) | DHODHKDM4ECYP2C9LMNACYP11B1 | |
| SCHEMBL10682024 | 0.81 | MAPT (0.49) | KDM4EALDH1A1MAPTHPGDCYP3A4 | |
| SCHEMBL7260213 | 0.79 | IDO1 (0.47) | DHODHKDM4EALDH1A1MAPTIDO1 | |
| SCHEMBL22201436 | 0.79 | PRKCH (0.52) | PRKCHPRKCEDHODHKDM4EALDH1A1 | |
| SCHEMBL16436810 | 0.77 | PRKCH (0.51) | PRKCHPRKCEDHODHKDM4EALDH1A1 | |
| SCHEMBL10674917 | 0.77 | DHODH (0.61) | DHODHKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL10882283 | 0.77 | KDM4E (0.52) | PRKCHPRKCEDHODHKDM4EALDH1A1 | |
| SCHEMBL8272630 | 0.77 | SYK (0.52) | KDM4EALDH1A1MAPTHPGDCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687018-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2012-01-25 | — | — | EP | disclosed |
| WO-2005046712-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-05-26 | — | — | WO | disclosed |