Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8294119 | 0.91 | CYP19A1 (0.41) | CYP19A1ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL12600692 | 0.80 | F2 (0.46) | CYP19A1ALDH1A1TSHRHTT | |
| SCHEMBL23204888 | 0.76 | CYP19A1 (0.36) | CYP19A1ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL14668111 | 0.75 | SMN1; SMN2 (0.38) | CYP19A1ALDH1A1SMN1; SMN2CNR2CNR1 | |
| SCHEMBL17702632 | 0.74 | ALDH1A1 (0.48) | ALDH1A1KMT2AKDM4E | |
| SCHEMBL4164840 | 0.74 | CYP19A1 (0.35) | CYP19A1ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1774288 | 0.73 | MEN1 (0.42) | CYP19A1ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL23697813 | 0.73 | MEN1 (0.42) | CYP19A1ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL15821045 | 0.73 | SMN1; SMN2 (0.37) | CYP19A1ALDH1A1SMN1; SMN2CNR2CNR1 | |
| SCHEMBL29324951 | 0.73 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2KMT2ARAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730142-B1 | NOVEL KETOAMIDES WITH CYCLIC P4'S AS INHIBITORS OF NS3 SERINE PROTEASE OF HEPATITIS C VIRUS | SCHERING CORP (US) | 2011-06-29 | — | — | EP | disclosed |
| WO-2005021584-A2 | NOVEL PEPTIDOMIMETIC NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS | SCHERING CORPORATION (US) | 2005-03-10 | — | — | WO | disclosed |