Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CD44 | P16070 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8611564 | 0.79 | GAA (0.46) | CA12CA9GAACD44CYP3A4 | |
| SCHEMBL8291602 | 0.77 | CA12 (0.36) | CA12CA9GAACA1CA2 | |
| SCHEMBL8296840 | 0.73 | GRIA1 (0.53) | CA12CA9PMP22SMN1; SMN2KMT2A | |
| SCHEMBL8291724 | 0.73 | KDM4E (0.47) | CA12CA9GAACA1CA2 | |
| SCHEMBL8292037 | 0.73 | GRIA1 (0.44) | CA12CA9GAACA1CA2 | |
| SCHEMBL4640129 | 0.69 | GAA (0.52) | CA12CA9GAACD44CYP3A4 | |
| SCHEMBL8291690 | 0.68 | KMT2A (0.44) | CA12CA9GAACA1CA2 | |
| SCHEMBL6171984 | 0.63 | MAPT (0.54) | CYP3A4KMT2AALDH1A1MAPTALOX15 | |
| SCHEMBL11830148 | 0.63 | GAA (0.46) | CA12CA9GAACD44CYP3A4 | |
| SCHEMBL30758081 | 0.63 | GAA (0.46) | CA12CA9GAACD44CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0676397-B1 | Oxopyridinylquinoxaline derivatives | SHIONOGI & CO (JP) | 1999-10-20 | — | — | EP | disclosed |
| CN-1044241-C | Oxopyridinylquinoxaline derivative | SHIONOGI & CO (JP) | 1999-07-21 | — | — | CN | disclosed |
| US-5677305-A | NERVOUS SYSTEM DISORDERS | SHIONOGI & CO., LTD. (JP) | 1997-10-14 | — | — | US | disclosed |
| CN-1123792-A | Oxopyridinylquinoxaline derivative | SHIONOGI & CO (JP) | 1996-06-05 | — | — | CN | disclosed |
| EP-0676397-A1 | Oxopyridinylquinoxaline derivatives | SHIONOGI & CO., LTD. (JP) | 1995-10-11 | — | — | EP | disclosed |