Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 6/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30782657 | 0.83 | ALDH1A1 (0.52) | ALDH1A1MAPTRAD51KMT2AMEN1 | |
| SCHEMBL15925956 | 0.83 | ALDH1A1 (0.52) | ALDH1A1MAPTRAD51KMT2AMEN1 | |
| SCHEMBL24756051 | 0.80 | ALDH1A1 (0.55) | ALDH1A1MAPTRAD51KMT2AMEN1 | |
| SCHEMBL24757867 | 0.80 | ALDH1A1 (0.59) | ALDH1A1MAPTRAD51KMT2AMEN1 | |
| SCHEMBL24756022 | 0.80 | ALDH1A1 (0.55) | ALDH1A1MAPTRAD51KMT2AMEN1 | |
| SCHEMBL897147 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MAPTRAD51KMT2AMEN1 | |
| SCHEMBL31728525 | 0.78 | ALDH1A1 (0.56) | ALDH1A1MAPTRAD51KMT2AMEN1 | |
| SCHEMBL15890256 | 0.78 | ALDH1A1 (0.60) | ALDH1A1MAPTRAD51KMT2AMEN1 | |
| SCHEMBL1010493 | 0.78 | ALDH1A1 (0.56) | ALDH1A1MAPTRAD51KMT2AMEN1 | |
| SCHEMBL896599 | 0.78 | ALDH1A1 (0.56) | ALDH1A1MAPTRAD51KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508469-B1 | 3,4,N-Trisubstituted-4,5-dihydro-1H-pyrazole-1-carboxamides and their use as insecticides | DOWELANCO (US) | 1999-03-03 | — | — | EP | disclosed |
| US-5493024-A | 1,2-DIARYL-2-PROPEN-1-ONE CHEMICAL INTERMEDIATE COMPOUND | DOWELANCO (US) | 1996-02-20 | — | — | US | disclosed |
| US-5250532-A | Moths. termites | DOWELANCO (US) | 1993-10-05 | — | — | US | disclosed |
| CN-1067426-A | 3,4, N-three replaces-4,5-dihydro-1 h-pyrazole-1-methane amide and they application as sterilant | DOWELANCO (US) | 1992-12-30 | — | — | CN | disclosed |
| EP-0508469-A1 | 3,4,N-Trisubstituted-4,5-dihydro-1H-pyrazole-1-carboxamides and their use as insecticides | DOWELANCO (US) | 1992-10-14 | — | — | EP | disclosed |