Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MARK4 | Q96L34 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | MBD2 | Q9UBB5 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2092577 | 0.90 | MAPT (0.44) | MAPTRAB9AALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL2094210 | 0.68 | ALDH1A1 (0.51) | MAPTRAB9AALDH1A1KMT2AMARK4 | |
| SCHEMBL1827846 | 0.66 | PTGS1 (0.40) | MAPTRAB9AALDH1A1MAPK1PKM | |
| SCHEMBL17620582 | 0.65 | RAD51 (0.47) | MAPTRAB9AALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL1852148 | 0.64 | MAPT (0.54) | MAPTRAB9AALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL23495290 | 0.63 | ALDH1A1 (0.58) | MAPTALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL4427347 | 0.63 | ALDH1A1 (0.55) | MAPTALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL28350522 | 0.63 | ALDH1A1 (0.50) | MAPTRAB9AALDH1A1L3MBTL1KMT2A | |
| SCHEMBL2320664 | 0.63 | CA1 (0.56) | MAPTALDH1A1MAPK1KIF11POLB | |
| SCHEMBL27444638 | 0.63 | MAPK1 (0.67) | MAPTRAB9AALDH1A1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009539-A2 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS, CORP. (US) | 2005-02-03 | — | — | WO | disclosed |