Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 8/20 | 0.52 |
| ▸ | MCHR2 | Q969V1 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | TACR2 | P21452 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14519566 | 1.00 | MEN1 (0.52) | MEN1KMT2APOLBMCHR1MCHR2 | |
| SCHEMBL14519469 | 0.89 | HTR3A (0.56) | MEN1KMT2APOLBMCHR1 | |
| SCHEMBL8297592 | 0.89 | HTR3A (0.56) | MEN1KMT2APOLBMCHR1 | |
| SCHEMBL8297052 | 0.88 | MEN1 (0.51) | MEN1KMT2APOLBMCHR1MCHR2 | |
| SCHEMBL5407336 | 0.84 | SMN1; SMN2 (0.55) | MEN1KMT2APOLBMCHR1MCHR2 | |
| SCHEMBL5407347 | 0.84 | SMN1; SMN2 (0.55) | MEN1KMT2APOLBMCHR1MCHR2 | |
| SCHEMBL5417157 | 0.84 | TACR2 (0.56) | MEN1KMT2APOLBMCHR1MCHR2 | |
| SCHEMBL5417153 | 0.84 | TACR2 (0.56) | MEN1KMT2APOLBMCHR1MCHR2 | |
| SCHEMBL8296130 | 0.81 | MAPK1 (0.50) | MCHR1SMN1; SMN2MAPK1CYP2C9CYP2C19 | |
| SCHEMBL14519567 | 0.81 | MAPK1 (0.50) | MCHR1SMN1; SMN2MAPK1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005044810-A1 | GLYT2 MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-05-19 | — | — | WO | disclosed |