Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 16/20 | 0.40 |
| ▸ | CTSB | P07858 | 10/20 | 0.40 |
| ▸ | CTSL | P07711 | 5/20 | 0.40 |
| ▸ | CTSK | P43235 | 8/20 | 0.38 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3621114 | 1.00 | CTSS (0.40) | CTSSCTSBCTSLCTSKCTSF | |
| SCHEMBL5605240 | 0.88 | CTSS (0.39) | CTSSCTSBCTSLCTSK | |
| SCHEMBL3625348 | 0.85 | CTSS (0.37) | CTSSCTSBCTSLCTSKCTSF | |
| SCHEMBL3618556 | 0.85 | CTSS (0.45) | CTSSCTSBCTSLCTSKCTSF | |
| SCHEMBL3618554 | 0.85 | CTSS (0.45) | CTSSCTSBCTSLCTSKCTSF | |
| SCHEMBL6745245 | 0.84 | CTSS (0.43) | CTSSCTSBCTSLCTSK | |
| SCHEMBL6745241 | 0.84 | CTSS (0.43) | CTSSCTSBCTSLCTSK | |
| SCHEMBL3615923 | 0.83 | CTSS (0.47) | CTSSCTSBCTSLCTSK | |
| SCHEMBL3621118 | 0.82 | CTSS (0.32) | CTSSCTSLCTSK | |
| SCHEMBL6740829 | 0.82 | CTSS (0.48) | CTSSCTSBCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662849-B2 | Amidino compounds as cysteine protease inhibitors | VIROBAY, INC. (US) | 2010-02-16 | — | — | US | disclosed |
| US-7662849-B2 | Amidino compounds as cysteine protease inhibitors | VIROBAY, INC. (US) | 2010-02-16 | — | — | US | disclosed |
| WO-2004108661-A1 | AMIDINO COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS (US) | 2004-12-16 | — | — | WO | disclosed |