Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 13/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7362803 | 0.87 | PDE5A (0.53) | PDE5AGAALMNAHPGD | |
| SCHEMBL8292287 | 0.85 | GAA (0.57) | GAALMNAHPGD | |
| SCHEMBL8292604 | 0.85 | GAA (0.52) | PDE5AGAALMNAHPGD | |
| SCHEMBL6944281 | 0.84 | GAA (0.55) | GAALMNAHPGD | |
| SCHEMBL8299247 | 0.82 | PDE5A (0.53) | PDE5AGAALMNAHPGD | |
| SCHEMBL7502173 | 0.81 | PDE5A (0.48) | PDE5AGAALMNAHPGD | |
| SCHEMBL8292510 | 0.81 | AKR1B1 (0.51) | LMNAHPGD | |
| SCHEMBL8296843 | 0.80 | PDE5A (0.44) | PDE5AGAALMNAHPGD | |
| SCHEMBL8296856 | 0.80 | PDE5A (0.44) | PDE5AGAALMNAHPGD | |
| SCHEMBL7371272 | 0.80 | PDE5A (0.47) | PDE5AGAALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686625-B1 | ANTHRANILIC ACID DERIVATIVE | EISAI CO LTD (JP) | 1999-05-26 | — | — | EP | disclosed |
| US-5716993-A | PHOSPHODIESTERASE ENZYME INHIBITOR FOR TREATING CARDIOVASCULAR DISORDER, ANGINA PECTORIS, HYPERTENSION, ASTHMA | EISAI CO., LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0686625-A1 | ANTHRANILIC ACID DERIVATIVE | Eisai Co., Ltd. (JP) | 1995-12-13 | — | — | EP | disclosed |