Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 10/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | WDR5 | P61964 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6941529 | 0.92 | LMNA (0.50) | PDE5ALMNAHPGDAKR1B1WDR5 | |
| SCHEMBL6941632 | 0.90 | ALDH1A1 (0.53) | LMNAWDR5 | |
| SCHEMBL7366039 | 0.90 | ALDH1A1 (0.53) | LMNAHPGDAKR1B1WDR5 | |
| SCHEMBL7366361 | 0.88 | LMNA (0.44) | LMNAHPGDAKR1B1WDR5 | |
| SCHEMBL8299255 | 0.87 | PDE5A (0.53) | PDE5AGAALMNAHPGD | |
| SCHEMBL6943273 | 0.82 | PPARA (0.55) | PDE5AGAALMNAHPGD | |
| SCHEMBL1585401 | 0.81 | PDPK1 (0.50) | AKR1B1WDR5 | |
| SCHEMBL7502173 | 0.81 | PDE5A (0.48) | PDE5AGAALMNAHPGD | |
| SCHEMBL6938883 | 0.80 | MEN1 (0.53) | PDE5AGAALMNAHPGDAKR1B1 | |
| SCHEMBL7371272 | 0.80 | PDE5A (0.47) | PDE5AGAALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001030745-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-03 | — | — | WO | disclosed |