Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 7/20 | 0.37 |
| ▸ | ACE | P12821 | 6/20 | 0.37 |
| ▸ | REN | P00797 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PEPD | P12955 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8301495 | 0.91 | ACE (0.40) | FKBP1AACERENKDM4EF2 | |
| SCHEMBL8300130 | 0.90 | ACE (0.39) | FKBP1AACERENKDM4EF2 | |
| SCHEMBL8303782 | 0.90 | ACE (0.39) | FKBP1AACERENKDM4EF2 | |
| SCHEMBL8303777 | 0.89 | FKBP1A (0.38) | FKBP1AACERENKDM4EF2 | |
| SCHEMBL8303032 | 0.89 | ACE (0.38) | FKBP1AACERENKDM4EF2 | |
| SCHEMBL8303029 | 0.89 | FKBP1A (0.38) | FKBP1AACERENKDM4EF2 | |
| SCHEMBL8301539 | 0.88 | FKBP1A (0.41) | FKBP1AACEREN | |
| SCHEMBL8304369 | 0.87 | ACE (0.37) | FKBP1AACERENKDM4EF2 | |
| SCHEMBL8303780 | 0.85 | FKBP1A (0.36) | FKBP1AACERENKDM4EF2 | |
| SCHEMBL8301523 | 0.85 | FKBP1A (0.36) | FKBP1AACERENKDM4EF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106300-A1 | CAPTOPRIL DERIVATIVES | NICOX S.A. (FR) | 2004-12-09 | — | — | WO | disclosed |