Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | PEPD | P12955 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL554115 | 0.75 | — | — | |
| SCHEMBL29044900 | 0.73 | — | — | |
| SCHEMBL5708449 | 0.73 | TSHR (0.43) | SLC7A5 | |
| SCHEMBL28623541 | 0.70 | — | — | |
| SCHEMBL420625 | 0.70 | — | — | |
| SCHEMBL28623543 | 0.70 | — | — | |
| SCHEMBL10710402 | 0.70 | PEPD (0.34) | PEPD | |
| SCHEMBL9773602 | 0.70 | ALOX15 (0.34) | SLC7A5GRIK1GRIK2GRM1GRM2 | |
| SCHEMBL25382932 | 0.68 | TSHR (0.33) | PEPD | |
| SCHEMBL27046 | 0.68 | MAPT (0.37) | PEPD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005011602-A2 | COMBINATION OF DEHYDROEPIANDROSTERONE OR DEHYDROEPIANDROSTERONE-SULFATE WITH A PDE-4 INHIBITOR FOR TREATMENT OF ASTHMA OR CHRONIC OBSTRUCTIVE PULMONARY DISEASE | EPIGENESIS PHARMACEUTICALS LLC (US) | 2005-02-10 | — | — | WO | disclosed |