Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13958546 | 0.91 | F10 (0.59) | F10 | |
| SCHEMBL8298336 | 0.91 | F10 (0.48) | F10 | |
| SCHEMBL5691287 | 0.87 | F10 (0.60) | F10FPR2 | |
| SCHEMBL4499412 | 0.80 | F10 (0.49) | F10 | |
| SCHEMBL4513597 | 0.79 | F10 (0.56) | F10 | |
| SCHEMBL4487761 | 0.77 | F10 (0.43) | F10FPR2 | |
| SCHEMBL13958541 | 0.76 | FPR2 (0.40) | F10FPR2 | |
| SCHEMBL6365157 | 0.75 | F10 (0.64) | F10 | |
| SCHEMBL5459134 | 0.75 | F10 (0.44) | F10FPR2 | |
| SCHEMBL5710344 | 0.75 | F10 (0.44) | F10FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482374-B2 | Pyrrolidine-2-ones as Factor Xa inhibitors | GLAXO GROUP LIMITED (GB) | 2009-01-27 | — | — | US | disclosed |
| US-7482374-B2 | Pyrrolidine-2-ones as Factor Xa inhibitors | GLAXO GROUP LIMITED (GB) | 2009-01-27 | — | — | US | disclosed |
| WO-2004111045-A1 | PYRROLIDINE - 2- ONES AS FACTOR XA INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-12-23 | — | — | WO | disclosed |