Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 2/20 | 0.62 |
| ▸ | GMNN | O75496 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | THPO | P40225 | 1/20 | 0.62 |
| ▸ | MTOR | P42345 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8294013 | 0.95 | GRIN2B (0.59) | GRIN2BGMNNTP53CYP3A4ALOX15 | |
| SCHEMBL8292488 | 0.92 | GRIN2B (0.62) | GRIN2BGMNNTP53CYP3A4ALOX15 | |
| SCHEMBL8442508 | 0.92 | GRIN2B (0.62) | GRIN2BGMNNTP53CYP3A4ALOX15 | |
| SCHEMBL8300325 | 0.90 | GRIN2B (0.63) | GRIN2BGMNNTP53CYP3A4ALOX15 | |
| SCHEMBL8297854 | 0.86 | GRIN2B (0.57) | GRIN2BGMNNTP53CYP3A4ALOX15 | |
| SCHEMBL27502384 | 0.83 | NTSR1 (0.48) | GRIN2BGMNNTP53CYP3A4ALOX15 | |
| SCHEMBL5973113 | 0.82 | POLB (0.59) | GRIN2BGMNNTP53CYP3A4ALOX15 | |
| SCHEMBL13122653 | 0.82 | POLB (0.59) | GRIN2BGMNNTP53CYP3A4ALOX15 | |
| SCHEMBL27502385 | 0.81 | GMNN (0.42) | GRIN2BGMNNTP53CYP3A4ALOX15 | |
| SCHEMBL1461382 | 0.81 | GMNN (0.55) | GRIN2BGMNNTP53CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0848707-B1 | 4-(CYCLOALKYL)PIPERIDINES AND 4-(CYCLOALKYLALKYL)-PIPERIDINES DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL APPLICATIONS THEREOF | SYNTHELABO (FR) | 1999-08-04 | — | — | EP | disclosed |
| EP-0848707-A1 | 4-(CYCLOALKYL)PIPERIDINES AND 4-(CYCLOALKYLALKYL)-PIPERIDINES DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL APPLICATIONS THEREOF | SYNTHELABO (FR) | 1998-06-24 | — | — | EP | disclosed |
| WO-1997009309-A1 | 4-(CYCLOALKYL)PIPERIDINE AND 4-(CYCLOALKYLALKYL)PIPERIDINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL APPLICATIONS THEREOF | SYNTHELABO (FR) | 1997-03-13 | — | — | WO | disclosed |