Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 15/20 | 0.47 |
| ▸ | TACR1 | P25103 | 14/20 | 0.47 |
| ▸ | TACR3 | P29371 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8292263 | 0.85 | TACR1 (0.44) | TACR2TACR1TACR3MCHR1SLC6A2 | |
| SCHEMBL8940496 | 0.83 | TACR2 (0.61) | TACR2TACR1TACR3 | |
| SCHEMBL8296720 | 0.83 | TACR2 (0.61) | TACR2TACR1TACR3 | |
| SCHEMBL8297274 | 0.79 | TACR2 (0.46) | TACR2TACR1TACR3 | |
| Citric Acid SCHEMBL8940305 | 0.78 | TACR2 (0.55) | TACR2TACR1TACR3 | |
| SCHEMBL8828923 | 0.71 | TACR2 (0.66) | TACR2TACR1TACR3 | |
| SCHEMBL8301140 | 0.71 | TACR2 (0.66) | TACR2TACR1TACR3 | |
| SCHEMBL8300377 | 0.71 | FPR3 (0.35) | — | |
| SCHEMBL8912293 | 0.71 | FPR3 (0.35) | — | |
| SCHEMBL8828992 | 0.70 | TACR2 (0.67) | TACR2TACR1TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726893-B1 | NOVEL 4-PIPERIDINYL SUBSTITUTED LACTAMES AS NEUROKININ 2 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF ASTHMA | ZENECA LTD (GB) | 1999-12-22 | — | — | EP | claimed |
| EP-0726893-B1 | NOVEL 4-PIPERIDINYL SUBSTITUTED LACTAMES AS NEUROKININ 2 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF ASTHMA | ZENECA LTD (GB) | 1999-12-22 | — | — | EP | disclosed |