Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
| ▸ | MIF | P14174 | 8/20 | 0.49 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23273172 | 0.91 | SRD5A1 (0.47) | SRD5A1SRD5A2MIFMAOBCYP26A1 | |
| SCHEMBL9390050 | 0.89 | SRD5A1 (0.57) | SRD5A1SRD5A2MIFMAOBCYP26A1 | |
| SCHEMBL9390046 | 0.89 | SRD5A1 (0.57) | SRD5A1SRD5A2MIFMAOBCYP26A1 | |
| SCHEMBL9390039 | 0.89 | SRD5A1 (0.57) | SRD5A1SRD5A2MIFMAOBCYP26A1 | |
| SCHEMBL17195434 | 0.82 | MIF (0.53) | MIFMAOBCYP26A1METAP1MAOA | |
| SCHEMBL14564405 | 0.82 | MIF (0.53) | MIFMAOBCYP26A1METAP1MAOA | |
| SCHEMBL14061927 | 0.79 | MIF (0.65) | MIFCYP26A1CYP19A1HTT | |
| SCHEMBL14137061 | 0.79 | MIF (0.65) | MIFCYP26A1CYP19A1HTT | |
| SCHEMBL4975289 | 0.79 | MIF (0.65) | MIFCYP26A1CYP19A1HTT | |
| SCHEMBL2601324 | 0.78 | METAP1 (0.60) | SRD5A1SRD5A2MIFCYP26A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0478195-B1 | Dihydropyridazinones and pyridazinones as fungicides | ROHM & HAAS (US) | 1999-05-26 | — | — | EP | disclosed |
| US-5753642-A | AGRICULTURE, MEDICINE | ROHM AND HAAS COMPANY (US) | 1998-05-19 | — | — | US | disclosed |
| US-5728698-A | AGRICULTURAL USE, RICE, WHEAT | ROHM AND HAAS COMPANY (US) | 1998-03-17 | — | — | US | disclosed |
| US-5728715-A | FOR MAMMALS, AGRICULTURE, RICE, WHEAT, TOMATOES | ROHM AND HAAS COMPANY (US) | 1998-03-17 | — | — | US | disclosed |
| US-5728694-A | Dihydropyridazinones, pyridazinones and related compounds as fungicides | ROHM AND HAAS COMPANY (US) | 1998-03-17 | — | — | US | disclosed |
| US-5726162-A | FOR CONTROLLING AGRICULTURAL AND MAMMALIAN FUNGAL DISEASES | ROHM AND HAAS COMPANY (US) | 1998-03-10 | — | — | US | disclosed |
| US-5726176-A | FOR CONTROLLING AGRICULTURAL AND MAMMALIAN FUNGAL DISEASES | ROHM AND HAAS COMPANY (US) | 1998-03-10 | — | — | US | disclosed |
| US-5631254-A | RICE; HUMAN INFECTIONS | ROHM AND HAAS COMPANY (US) | 1997-05-20 | — | — | US | disclosed |
| US-5552409-A | PHYTOPATHOGENIC, RICE | ROHM AND HAAS COMPANY (US) | 1996-09-03 | — | — | US | disclosed |
| EP-0478195-A1 | Dihydropyridazinones, pyridazinones and related compounds as fungicides | ROHM AND HAAS COMPANY (US) | 1992-04-01 | — | — | EP | disclosed |