SCHEMBL8300456

SCHEMBL8300456

CC1CCN(C(=O)O)[C@@H](C#N)C1

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 19/20 0.41
DPP8 Q6V1X1 3/20 0.38
DPP9 Q86TI2 3/20 0.38
PREP P48147 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8300453 1.00 DPP4 (0.41) DPP4DPP8DPP9PREP
SCHEMBL8540934 0.81 DPP4 (0.41) DPP4DPP8DPP9
SCHEMBL8540930 0.81 DPP4 (0.41) DPP4DPP8DPP9
SCHEMBL14834279 0.81
SCHEMBL16054584 0.81
SCHEMBL2016589 0.75 ALDH1A1 (0.35) DPP4
SCHEMBL2019290 0.75 ALDH1A1 (0.35)
SCHEMBL14899497 0.75 DPP7 (0.53) DPP4DPP8DPP9
SCHEMBL858699 0.73 DPP4 (0.59) DPP4DPP8DPP9PREP
SCHEMBL26094394 0.73 DPP4 (0.59) DPP4DPP8DPP9PREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0614986-B1 Enzymatic racemate cleavage of 2-pipéridine alkylcarboxylates SYNTHELABO (FR) 1999-07-21 EP disclosed
EP-0614986-A1 Enzymatic racemate cleavage of 2-pipéridine alkylcarboxylates and their use as synthesis intermediates SYNTHELABO (FR) 1994-09-14 EP disclosed