⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL725415 | 0.85 | LMNA (0.32) | — | |
| SCHEMBL17376990 | 0.83 | LMNA (0.31) | — | |
| SCHEMBL1015909 | 0.83 | LMNA (0.33) | — | |
| SCHEMBL28393677 | 0.81 | LMNA (0.32) | — | |
| SCHEMBL30199666 | 0.81 | LMNA (0.32) | — | |
| SCHEMBL2587473 | 0.74 | APP (0.37) | — | |
| SCHEMBL1832184 | 0.73 | LMNA (0.38) | — | |
| SCHEMBL1938659 | 0.72 | APP (0.38) | — | |
| SCHEMBL355936 | 0.70 | DPP7 (0.34) | — | |
| SCHEMBL8105495 | 0.70 | LMNA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948663-A | THE PRESENT INVENTION RELATES TO A THERMOSTABLE ENZYME HAVING DNA POLYMERASE I ACTIVITY USEFUL IN NUCLEIC ACID SYNTHESIS BY PRIMER EXTENSION REACTION. | STRATAGENE (US) | 1999-09-07 | — | — | US | disclosed |
| US-5866395-A | BACTERIOPHAGE | STRATAGENE (US) | 1999-02-02 | — | — | US | disclosed |