Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2944484 | 0.86 | L3MBTL1 (0.50) | L3MBTL1NPSR1HDAC3HDAC1HDAC2 | |
| SCHEMBL1913578 | 0.85 | L3MBTL1 (0.49) | L3MBTL1NPSR1HDAC3HDAC1HDAC2 | |
| SCHEMBL1913579 | 0.85 | L3MBTL1 (0.49) | L3MBTL1NPSR1HDAC3HDAC1HDAC2 | |
| SCHEMBL7616466 | 0.84 | L3MBTL1 (0.51) | L3MBTL1NPSR1HDAC3HDAC1HDAC2 | |
| SCHEMBL10667221 | 0.84 | L3MBTL1 (0.46) | L3MBTL1NPSR1HDAC3HDAC1HDAC2 | |
| SCHEMBL10473063 | 0.84 | L3MBTL1 (0.46) | L3MBTL1NPSR1HDAC3HDAC1HDAC2 | |
| SCHEMBL8362357 | 0.83 | L3MBTL1 (0.47) | L3MBTL1NPSR1HDAC3HDAC1HDAC2 | |
| SCHEMBL15318912 | 0.83 | L3MBTL1 (0.47) | L3MBTL1NPSR1HDAC3HDAC1HDAC2 | |
| SCHEMBL15318910 | 0.83 | L3MBTL1 (0.47) | L3MBTL1NPSR1HDAC3HDAC1HDAC2 | |
| SCHEMBL1711414 | 0.82 | L3MBTL1 (0.50) | L3MBTL1NPSR1HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5969135-A | COMPOUNDS FOR USE AS ANTISENSE CONTROL OF GENE EXPRESSION AND HYBRIDIZATION | ICN PHARMACEUTICALS, INC. (US) | 1999-10-19 | — | — | US | disclosed |
| EP-0789707-A4 | AMINO ACID NUCLEIC ACIDS | ICN PHARMACEUTICALS (US) | 1999-02-24 | — | — | EP | disclosed |
| EP-0789707-A1 | AMINO ACID NUCLEIC ACIDS | ICN PHARMACEUTICALS (US) | 1997-08-20 | — | — | EP | disclosed |
| WO-1996014330-A1 | AMINO ACID NUCLEIC ACIDS | ICNPHARMACEUTICALS (US) | 1996-05-17 | — | — | WO | disclosed |