SCHEMBL8300827

SCHEMBL8300827

CCCCCCCCCCCCOc1ccc(-c2ccc(C(=O)O)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
RARB P10826 5/20 1.00
TP53 P04637 1/20 0.90
TSHR P16473 1/20 0.90
PLA2G4B P0C869 8/20 0.88
PLA2G4A P47712 1/20 0.78
PTPN11 Q06124 2/20 0.71
HTT P42858 1/20 0.68
PLA2G2A P14555 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2354189 1.00 RARB (1.00) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL7172427 1.00 RARB (1.00) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL8535621 1.00 RARB (1.00) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL8943017 1.00 RARB (1.00) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL8532269 1.00 RARB (1.00) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL641904 1.00 RARB (1.00) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL4185457 1.00 RARB (1.00) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL5828640 1.00 RARB (1.00) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL5858775 1.00 RARB (1.00) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL2038307 1.00 RARB (1.00) RARBTP53TSHRPLA2G4BPLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0327349-B1 Liquid crystal compounds SHOWA SHELL SEKIYU (JP) 1996-04-10 EP claimed
EP-0630892-B1 Chiral compounds BASF AG (DE) 1999-11-17 EP disclosed
US-5776365-A COMPOUNDS WITH OPTICAL ACTIVITY AND SWITCHES FOR CONTRAST MITSUI CHEMICALS, INC. (JP) 1998-07-07 US disclosed
US-5725798-A CARBOXYLIC ESTERS FOR ELECTRICAL APPARATUS, SWITCHES AND CONTRAST MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-03-10 US disclosed
EP-0549347-B1 Novel carboxylate compounds, liquid crystal materials, liquid crystal compositions and liquid crystal elements MITSUI PETROCHEMICAL IND (JP) 1997-10-29 EP disclosed
US-5571920-A Alcohols HOFFMANN-LA ROCHE INC. (US) 1996-11-05 US disclosed
US-5554756-A PROTEASE INHIBITOR HOFFMANN-LA ROCHE INC. (US) 1996-09-10 US disclosed
EP-0579770-B1 MACROCYCLIC LACTAM PROKINETIC AGENTS ABBOTT LAB (US) 1996-06-26 EP disclosed
EP-0571277-B1 Antiferroelectric liquid crystal compound SHOWA SHELL SEKIYU (JP) 1996-06-26 EP disclosed
US-5516913-A Alcohols HOFFMANN-LA ROCHE INC. (US) 1996-05-14 US disclosed
EP-0402233-A1 Liquid crystal compounds Showa Shell Sekiyu Kabushiki Kaisha (JP) 1990-12-12 EP disclosed
US-4943386-A FERROELECTRIC, GOOD RESPONSE AND MEMORY DAINIPPON INK & CHEMICALS, INC. (JP) 1990-07-24 US disclosed
US-4918213-A HAVING A TRIFLUOROMETHYL GROUP ATTACHED TO ASYMMETRIC CARBON ATOM; STABLE; OPTICAL DEVICES CANON KABUSHIKI KAISHA (JP) 1990-04-17 US disclosed
US-4886623-A Ferroelectric smectic liquid crystal compound and composition containing the same TAKASAGO INTERNATIONAL CORPORATION (JP) 1989-12-12 US disclosed
US-4828754-A TILT-TYPE CHIRAL SMECTIC PHASE DAINIPPON INK & CHEMICALS, INC. (JP) 1989-05-09 US disclosed
EP-0311692-A1 NOVEL ALKANOYL ESTER COMPOUNDS, INTERMEDIATES THEREFOR, AND PROCESSES FOR THEIR PREPARATION NIPPON MINING COMPANY LIMITED (JP) 1989-04-19 EP disclosed
EP-0304320-A2 Fluorine-containing liquid crystal compound Takasago International Corporation (JP) 1989-02-22 EP disclosed
EP-0301511-A1 Optically active compound and liquid crystal composition containing same CANON KABUSHIKI KAISHA (JP) 1989-02-01 EP disclosed
EP-0255962-A2 Optically active mesomorphic compound CANON KABUSHIKI KAISHA (JP) 1988-02-17 EP disclosed
EP-0188222-A2 Novel liquid cristalline compounds having substituents DAINIPPON INK AND CHEMICALS, INC. (JP) 1986-07-23 EP disclosed