SCHEMBL8943017

SCHEMBL8943017

CCCCCCCCCCCCCCCCOc1ccc(-c2ccc(C(=O)O)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
RARB P10826 5/20 1.00
TP53 P04637 1/20 0.90
TSHR P16473 1/20 0.90
PLA2G4B P0C869 8/20 0.88
PLA2G4A P47712 1/20 0.78
PTPN11 Q06124 2/20 0.71
HTT P42858 1/20 0.68
PLA2G2A P14555 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2354189 1.00 RARB (1.00) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL7172427 1.00 RARB (1.00) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL8535621 1.00 RARB (1.00) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL8300827 1.00 RARB (1.00) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL8532269 1.00 RARB (1.00) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL641904 1.00 RARB (1.00) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL4185457 1.00 RARB (1.00) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL5828640 1.00 RARB (1.00) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL5858775 1.00 RARB (1.00) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL2038307 1.00 RARB (1.00) RARBTP53TSHRPLA2G4BPLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0467721-B1 Optically active compound having a delta- valerolactone ring and liquid crystal composition containing same MITSUBISHI RAYON CO (JP) 1996-03-27 EP disclosed
US-5480580-A COMPOUNDS FOR VISUAL AIDS WITH GOOD STABILITY MITSUBISHI RAYON COMPANY LTD. (JP) 1996-01-02 US disclosed
EP-0440134-B1 Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus CANON KK (JP) 1994-09-21 EP disclosed
US-5217644-A MESOMORPHIC COMPOUND, LIQUID CRYSTAL COMPOSITION CONTAINING SAME, LIQUID CRYSTAL DEVICE USING SAME AND DISPLAY APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-06-08 US disclosed
US-5139696-A Hydrogen-bonded liquid crystal complexes CORNELL RESEARCH FOUNDATION, INC. (US) 1992-08-18 US disclosed
EP-0188222-B1 NOVEL LIQUID CRISTALLINE COMPOUNDS HAVING SUBSTITUENTS DAINIPPON INK AND CHEMICALS, INC. (JP) 1992-04-29 EP disclosed
EP-0467721-A1 Optically active compound having a delta- valerolactone ring and liquid crystal composition containing same MITSUBISHI RAYON CO., LTD (JP) 1992-01-22 EP disclosed
EP-0440134-A1 Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus CANON KABUSHIKI KAISHA (JP) 1991-08-07 EP disclosed
US-5037574-A Hydrogen-bonded liquid crystal complexes CORNELL RESEARCH FOUNDATION, INC. (US) 1991-08-06 US disclosed
US-4943386-A FERROELECTRIC, GOOD RESPONSE AND MEMORY DAINIPPON INK & CHEMICALS, INC. (JP) 1990-07-24 US disclosed
US-4886623-A Ferroelectric smectic liquid crystal compound and composition containing the same TAKASAGO INTERNATIONAL CORPORATION (JP) 1989-12-12 US disclosed
US-4828754-A TILT-TYPE CHIRAL SMECTIC PHASE DAINIPPON INK & CHEMICALS, INC. (JP) 1989-05-09 US disclosed
EP-0188222-A2 Novel liquid cristalline compounds having substituents DAINIPPON INK AND CHEMICALS, INC. (JP) 1986-07-23 EP disclosed