Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GPR183 | P32249 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 5/20 | 0.39 |
| ▸ | ALPI | P09923 | 5/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7221177 | 0.99 | CNR1 (0.39) | CNR1CNR2MEN1GPR183KMT2A | |
| SCHEMBL7228892 | 0.90 | CNR1 (0.41) | CNR1CNR2MEN1GPR183KMT2A | |
| SCHEMBL7227201 | 0.87 | CNR1 (0.38) | CNR1CNR2MEN1GPR183KMT2A | |
| SCHEMBL7228982 | 0.86 | CNR1 (0.44) | CNR1CNR2MEN1GPR183KMT2A | |
| SCHEMBL15345402 | 0.77 | DPP4 (0.47) | LOXL2CARM1PRMT6 | |
| SCHEMBL7227793 | 0.74 | MRGPRX1 (0.45) | CNR1CNR2MEN1KMT2AALPL | |
| SCHEMBL27692886 | 0.71 | ALPL (0.45) | CNR1CNR2MEN1KMT2AALPL | |
| SCHEMBL6706440 | 0.71 | CNR1 (0.41) | CNR1CNR2MEN1GPR183KMT2A | |
| SCHEMBL7220492 | 0.70 | CNR2 (0.64) | CNR1CNR2MEN1GPR183KMT2A | |
| SCHEMBL2362375 | 0.70 | HTR1B (0.47) | CNR1CNR2ALPLALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0966436-A1 | ARYL SULFONAMIDES AND ANALOGUES THEREOF AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | Bayer Aktiengesellschaft (DE) | 1999-12-29 | — | — | EP | disclosed |
| WO-1998037061-A1 | ARYL SULFONAMIDES AND ANALOGUES THEREOF AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-08-27 | — | — | WO | disclosed |