Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | PPARD | Q03181 | 4/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8306153 | 0.90 | NPC1 (0.46) | NPC1RAB9APPARGPPARAPOLB | |
| SCHEMBL8301557 | 0.89 | NPC1 (0.43) | NPC1RAB9AALDH1A1PPARGPPARD | |
| SCHEMBL8308030 | 0.78 | ITGB3 (0.48) | NPC1RAB9AALDH1A1PPARGPPARA | |
| SCHEMBL8307977 | 0.78 | PPARG (0.51) | PPARGPPARDPPARA | |
| SCHEMBL8302608 | 0.78 | NPC1 (0.43) | NPC1RAB9AALDH1A1PPARGPPARA | |
| SCHEMBL8302884 | 0.77 | PPARG (0.62) | PPARGPPARDPPARA | |
| SCHEMBL8305544 | 0.77 | PPARG (0.51) | PPARGPPARDPPARA | |
| SCHEMBL6948887 | 0.71 | PPARG (0.41) | PPARGPPARAITGB3ITGA2B | |
| SCHEMBL8304776 | 0.71 | NPC1 (0.45) | NPC1RAB9APPARGPPARDPPARA | |
| SCHEMBL8306718 | 0.70 | NPC1 (0.41) | NPC1RAB9APPARGPPARAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |