Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 2/20 | 0.56 |
| ▸ | TK2 | O00142 | 5/20 | 0.55 |
| ▸ | TK1 | P04183 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26034750 | 0.93 | TK2 (0.56) | TYMPTK2TK1MAPK1HPGD | |
| SCHEMBL23453029 | 0.89 | TYMP (0.59) | TYMPTK2TK1MAPK1HPGD | |
| SCHEMBL15110503 | 0.89 | TK2 (0.60) | TYMPTK2TK1MAPK1HPGD | |
| SCHEMBL26779948 | 0.84 | TK1 (0.60) | TYMPTK2TK1MAPK1HPGD | |
| SCHEMBL2496425 | 0.83 | HPGD (0.55) | TYMPTK2TK1MAPK1HPGD | |
| SCHEMBL5025559 | 0.83 | TK2 (0.55) | TYMPTK2TK1MAPK1HPGD | |
| SCHEMBL5025556 | 0.83 | TK2 (0.55) | TYMPTK2TK1MAPK1HPGD | |
| SCHEMBL13261412 | 0.83 | TK1 (0.62) | TYMPTK2TK1MAPK1HPGD | |
| SCHEMBL20743084 | 0.83 | TK2 (0.55) | TYMPTK2TK1MAPK1HPGD | |
| SCHEMBL7124047 | 0.83 | HPGD (0.55) | TYMPTK2TK1MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220440-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |
| WO-2022099159-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2022-05-12 | — | — | WO | disclosed |
| US-5969135-A | COMPOUNDS FOR USE AS ANTISENSE CONTROL OF GENE EXPRESSION AND HYBRIDIZATION | ICN PHARMACEUTICALS, INC. (US) | 1999-10-19 | — | — | US | disclosed |
| EP-0789707-A4 | AMINO ACID NUCLEIC ACIDS | ICN PHARMACEUTICALS (US) | 1999-02-24 | — | — | EP | disclosed |
| EP-0789707-A1 | AMINO ACID NUCLEIC ACIDS | ICN PHARMACEUTICALS (US) | 1997-08-20 | — | — | EP | disclosed |
| WO-1996014330-A1 | AMINO ACID NUCLEIC ACIDS | ICNPHARMACEUTICALS (US) | 1996-05-17 | — | — | WO | disclosed |