Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8301788 | 1.00 | POLB (0.46) | POLBKDM4ELMNASMN1; SMN2KMT2A | |
| SCHEMBL8416857 | 0.90 | NLRP3 (0.45) | POLBLMNAKMT2ANPC1HPGD | |
| SCHEMBL8416853 | 0.90 | NLRP3 (0.45) | POLBLMNAKMT2ANPC1HPGD | |
| SCHEMBL8292073 | 0.87 | NPC1 (0.47) | KDM4ELMNAKMT2ANPC1ALDH1A1 | |
| SCHEMBL8292075 | 0.87 | NPC1 (0.47) | KDM4ELMNAKMT2ANPC1ALDH1A1 | |
| SCHEMBL8293091 | 0.85 | NPC1 (0.46) | KDM4ELMNAKMT2ANPC1HPGD | |
| SCHEMBL8293088 | 0.85 | NPC1 (0.46) | KDM4ELMNAKMT2ANPC1HPGD | |
| SCHEMBL8301610 | 0.84 | PDE5A (0.45) | LMNAKMT2ANPC1ALDH1A1HPGD | |
| SCHEMBL8301612 | 0.84 | PDE5A (0.45) | LMNAKMT2ANPC1ALDH1A1HPGD | |
| SCHEMBL8293493 | 0.83 | PDE5A (0.53) | LMNANPC1HPGDPKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686625-B1 | ANTHRANILIC ACID DERIVATIVE | EISAI CO LTD (JP) | 1999-05-26 | — | — | EP | disclosed |
| US-5716993-A | PHOSPHODIESTERASE ENZYME INHIBITOR FOR TREATING CARDIOVASCULAR DISORDER, ANGINA PECTORIS, HYPERTENSION, ASTHMA | EISAI CO., LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0686625-A1 | ANTHRANILIC ACID DERIVATIVE | Eisai Co., Ltd. (JP) | 1995-12-13 | — | — | EP | disclosed |