Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ESRRA | P11474 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7419149 | 0.80 | JAK2 (0.53) | MAPTSMN1; SMN2HTTALDH1A1HSD17B10 | |
| SCHEMBL8429265 | 0.80 | SMN1; SMN2 (0.45) | MAPTSMN1; SMN2HTTHSP90AA1ALDH1A1 | |
| SCHEMBL8296815 | 0.80 | IP6K1 (0.51) | MAPTSMN1; SMN2HTTHSP90AA1ALDH1A1 | |
| SCHEMBL5734578 | 0.79 | MAPT (0.62) | MAPTSMN1; SMN2HTTHSP90AA1ALDH1A1 | |
| SCHEMBL1824296 | 0.73 | KDM4E (0.46) | MAPTSMN1; SMN2HTTHSP90AA1ALDH1A1 | |
| SCHEMBL268116 | 0.73 | IP6K1 (0.61) | MAPTSMN1; SMN2HTTALDH1A1HSD17B10 | |
| SCHEMBL2404051 | 0.72 | ALDH1A1 (0.64) | MAPTSMN1; SMN2HTTALDH1A1HSD17B10 | |
| SCHEMBL11581128 | 0.72 | ALDH1A1 (0.64) | MAPTSMN1; SMN2ALDH1A1HSD17B10RAB9A | |
| SCHEMBL31032735 | 0.72 | ALDH1A1 (0.64) | MAPTSMN1; SMN2HTTALDH1A1HSD17B10 | |
| SCHEMBL9073929 | 0.72 | ALDH1A1 (0.64) | MAPTSMN1; SMN2ALDH1A1HSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686625-B1 | ANTHRANILIC ACID DERIVATIVE | EISAI CO LTD (JP) | 1999-05-26 | — | — | EP | disclosed |
| US-5716993-A | PHOSPHODIESTERASE ENZYME INHIBITOR FOR TREATING CARDIOVASCULAR DISORDER, ANGINA PECTORIS, HYPERTENSION, ASTHMA | EISAI CO., LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| CN-1118595-A | Anthranilic acid derivative | EISAI CO LTD (JP) | 1996-03-13 | — | — | CN | disclosed |
| EP-0686625-A1 | ANTHRANILIC ACID DERIVATIVE | Eisai Co., Ltd. (JP) | 1995-12-13 | — | — | EP | disclosed |