Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.33 |
| ▸ | CRHBP | P24387 | 2/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 3/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6579076 | 0.91 | HDAC8 (0.41) | HDAC11HDAC8ALDH1A1CYP3A4TDP1 | |
| SCHEMBL6581152 | 0.84 | PLK1 (0.39) | KDM4ELMNACYP1A2CYP3A4TDP1 | |
| SCHEMBL6579059 | 0.84 | PLK1 (0.39) | KDM4ELMNACYP1A2CYP3A4TDP1 | |
| SCHEMBL6581131 | 0.81 | KDM4E (0.39) | KDM4EALDH1A1HPGDLMNACYP1A2 | |
| SCHEMBL6581118 | 0.80 | MAPT (0.37) | KDM4EALDH1A1HPGDTDP1SENP1 | |
| SCHEMBL6581270 | 0.78 | KMT2A (0.42) | KDM4EALDH1A1HPGDLMNACYP1A2 | |
| SCHEMBL6579763 | 0.78 | CA1 (0.44) | HDAC11HDAC8KDM4EALDH1A1HPGD | |
| SCHEMBL6579793 | 0.76 | CA1 (0.39) | KDM4EALDH1A1HPGDLMNASENP1 | |
| SCHEMBL6579509 | 0.76 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDLMNATDP1 | |
| SCHEMBL6582050 | 0.76 | PLK1 (0.37) | KDM4EALDH1A1HPGDLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |