Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8304798 | 0.87 | DRD4 (0.44) | DRD4HTR2A | |
| SCHEMBL8302001 | 0.86 | PARP1 (0.48) | — | |
| SCHEMBL8303613 | 0.86 | DRD4 (0.43) | DRD4HTR2A | |
| SCHEMBL8306615 | 0.83 | HTR2A (0.43) | DRD4HTR2A | |
| SCHEMBL8307680 | 0.81 | HTR2A (0.65) | DRD4HTR2A | |
| SCHEMBL8303832 | 0.81 | DRD4 (0.39) | DRD4HTR2A | |
| SCHEMBL9778524 | 0.78 | HTR2A (0.44) | HTR2A | |
| SCHEMBL8307413 | 0.78 | DRD4 (0.44) | DRD4HTR2A | |
| SCHEMBL8302548 | 0.76 | DRD4 (0.67) | DRD4HTR2A | |
| SCHEMBL8301640 | 0.75 | DRD4 (0.66) | DRD4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041445-A | Antipsychotic agents | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-08-20 | — | — | US | claimed |
| EP-0458234-B1 | 3-[1,Thiazolidinylbutyl-4-piperazinyl]-1H-indazoles, a process for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1999-03-31 | — | — | EP | disclosed |
| EP-0458234-A2 | 3-[1,Thiazolidinylbutyl-4-piperazinyl]-1H-indazoles, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-11-27 | — | — | EP | disclosed |
| US-5041445-A | Antipsychotic agents | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-08-20 | — | — | US | disclosed |