Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.44 |
| ▸ | RORC | P51449 | 3/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HPGDS | O60760 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8303730 | 1.00 | KDM4E (0.45) | KDM4EPKMUSP30RORCGPR119 | |
| SCHEMBL26301615 | 0.89 | KDM4E (0.50) | KDM4EPKMUSP30GPR119MEN1 | |
| SCHEMBL27400480 | 0.89 | KDM4E (0.46) | KDM4EPKMUSP30RORCGPR119 | |
| SCHEMBL21072534 | 0.86 | USP30 (0.54) | KDM4EPKMUSP30RORCGPR119 | |
| SCHEMBL21072537 | 0.86 | USP30 (0.54) | KDM4EPKMUSP30RORCGPR119 | |
| SCHEMBL21072536 | 0.86 | USP30 (0.54) | KDM4EPKMUSP30RORCGPR119 | |
| SCHEMBL21640298 | 0.85 | KDM4E (0.49) | KDM4EPKMUSP30RORCGPR119 | |
| SCHEMBL27160438 | 0.82 | RORC (0.46) | KDM4EPKMUSP30RORCGPR119 | |
| SCHEMBL27160443 | 0.82 | RORC (0.46) | KDM4EPKMUSP30RORCGPR119 | |
| SCHEMBL7670902 | 0.81 | GAA (0.47) | KDM4EPKMUSP30RORCGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005032541-A1 | SUBSTITUTED HETEROCYCLIC MERCAPTOSULFIDE INHIBITORS | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2005-04-14 | — | — | WO | disclosed |