Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8307352 | 0.99 | KDM4E (0.41) | KDM4EALDH1A1LMNAHSD17B10GLA | |
| SCHEMBL8306767 | 0.94 | KDM4E (0.38) | KDM4EALDH1A1LMNAHSD17B10GLA | |
| Hydrochloric Acid SCHEMBL6833309 | 0.93 | KDM4E (0.37) | KDM4EALDH1A1LMNAHSD17B10GLA | |
| SCHEMBL5723117 | 0.78 | PDE4A (0.36) | KDM4EALDH1A1LMNAGLAABCB1 | |
| SCHEMBL5722813 | 0.78 | KDM4E (0.34) | KDM4EALDH1A1LMNAGLAABCB1 | |
| Hydrochloric Acid SCHEMBL5723041 | 0.77 | PDE4A (0.35) | KDM4EALDH1A1LMNAGLAABCB1 | |
| SCHEMBL5723234 | 0.75 | PDE4B (0.37) | KDM4EALDH1A1LMNAGLAABCB1 | |
| SCHEMBL15988845 | 0.74 | KDM4E (0.66) | KDM4EALDH1A1LMNAHSD17B10L3MBTL1 | |
| SCHEMBL6609896 | 0.73 | LMNA (0.50) | KDM4EALDH1A1LMNAHSD17B10HTR2A | |
| SCHEMBL6839167 | 0.73 | LMNA (0.58) | KDM4EALDH1A1LMNAHSD17B10PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943613-A1 | OXYGENIC HETEROCYCLIC COMPOUNDS | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1999-09-22 | — | — | EP | disclosed |