Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 20/20 | 0.79 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | PROC | P04070 | 1/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | MASP2 | O00187 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Melagatran SCHEMBL23840802 | 0.89 | F2 (0.64) | F2F10PROCF7MASP2 | |
| Melagatran SCHEMBL27652 | 0.89 | F2 (0.64) | F2F10PROCF7MASP2 | |
| SCHEMBL14509424 | 0.89 | F2 (0.64) | F2F10PROCF7PLAT | |
| Melagatran SCHEMBL8083301 | 0.89 | F2 (0.64) | F2F10PROCF7MASP2 | |
| Melagatran SCHEMBL20567754 | 0.89 | F2 (0.64) | F2F10PROCF7MASP2 | |
| Melagatran SCHEMBL5706395 | 0.89 | F2 (0.63) | F2F10PROCF7MASP2 | |
| Melagatran SCHEMBL3209070 | 0.89 | F2 (0.63) | F2F10PROCF7MASP2 | |
| Melagatran SCHEMBL29160734 | 0.89 | F2 (0.63) | F2F10PROCF7MASP2 | |
| Melagatran SCHEMBL27557537 | 0.89 | F2 (0.63) | F2F10PROCF7MASP2 | |
| Ximelagatran SCHEMBL14509860 | 0.88 | F2 (1.00) | F2F10PLATPRSS1MASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004113364-A1 | NEW PROCESS FOR THE PRODUCTION OF MELAGATRAN | ASTRAZENECA AB (SE) | 2004-12-29 | — | — | WO | disclosed |