Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1379573 | 0.91 | APP (0.39) | APPTDP1KMT2AMEN1MAPT | |
| SCHEMBL1379571 | 0.91 | APP (0.39) | APPTDP1KMT2AMEN1MAPT | |
| SCHEMBL5144162 | 0.83 | APP (0.39) | APPTDP1KMT2AMEN1MAPT | |
| SCHEMBL1379587 | 0.82 | APP (0.41) | APPTDP1KMT2AMEN1MAPT | |
| SCHEMBL1379586 | 0.82 | APP (0.41) | APPTDP1KMT2AMEN1MAPT | |
| SCHEMBL1376041 | 0.82 | MAPT (0.47) | APPKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL1376039 | 0.82 | MAPT (0.47) | APPKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL1376394 | 0.81 | APP (0.42) | APPKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL1375570 | 0.81 | APP (0.40) | APPKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL1376393 | 0.81 | APP (0.42) | APPKMT2AMEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005011812-A1 | CYANOAMIDE COMPOUNDS USEFUL AS MALONYL-COA DECARBOXYLASE INHIBITHORS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2005-02-10 | — | — | WO | disclosed |