Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.52 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.51 |
| ▸ | PREP | P48147 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15607552 | 0.96 | ACE2 (0.55) | CTSKACE2PREPALDH1A1 | |
| SCHEMBL14646609 | 0.86 | NPC1 (0.60) | ACE2FKBP1APREPTMEM97SIGMAR1 | |
| SCHEMBL13198885 | 0.86 | NPC1 (0.60) | ACE2FKBP1APREPTMEM97SIGMAR1 | |
| SCHEMBL13661115 | 0.85 | SMN1; SMN2 (0.52) | FKBP1ATMEM97SIGMAR1 | |
| SCHEMBL13994810 | 0.85 | PREP (0.57) | ACE2PREPALDH1A1 | |
| SCHEMBL791439 | 0.85 | PREP (0.57) | ACE2PREPALDH1A1 | |
| SCHEMBL3604619 | 0.85 | FKBP1A (0.51) | CTSKCTSBCTSSACE2FKBP1A | |
| SCHEMBL3605585 | 0.85 | SPHK2 (0.54) | ACE2FKBP1APREPTMEM97SIGMAR1 | |
| SCHEMBL1190565 | 0.85 | SPHK2 (0.54) | ACE2FKBP1APREPTMEM97SIGMAR1 | |
| SCHEMBL80752 | 0.85 | SPHK2 (0.54) | ACE2FKBP1APREPTMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0614986-B1 | Enzymatic racemate cleavage of 2-pipéridine alkylcarboxylates | SYNTHELABO (FR) | 1999-07-21 | — | — | EP | disclosed |