SCHEMBL8303488

SCHEMBL8303488

CCCCCCCCCCCCCCCCCCNC(=O)OCC1(CO)CSC1

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.49
ACHE P22303 11/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8307698 0.84 EPHX1 (0.50) EPHX1ACHE
SCHEMBL8304388 0.84 EPHX1 (0.50) EPHX1ACHE
SCHEMBL8304959 0.83 EPHX1 (0.49) EPHX1ACHE
SCHEMBL8305773 0.79 ZDHHC2 (0.49)
SCHEMBL12039681 0.77 EPHX1 (0.51) EPHX1ACHE
SCHEMBL8308759 0.76 HPGD (0.47)
SCHEMBL8887825 0.74 EPHX1 (0.47) EPHX1ACHE
SCHEMBL19677625 0.73 EPHX1 (0.68) EPHX1ACHE
SCHEMBL10544589 0.73 EPHX1 (0.46) EPHX1ACHE
SCHEMBL2987259 0.71 EPHX1 (0.70) EPHX1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0607374-B1 NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS PO HANG IRON & STEEL (KR) 1999-04-07 EP disclosed
US-5610310-A Cyclic lipid derivatives as potent PAF antagonists POHANG IRON & STEEL CO., LTD (KR) 1997-03-11 US disclosed
EP-0607374-A1 NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS POHANG IRON & STEEL CO., LTD. (KR) 1994-07-27 EP disclosed
WO-1994000447-A1 NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS POHANG IRON & STEEL CO., LTD. (KR) 1994-01-06 WO disclosed