SCHEMBL8307698

SCHEMBL8307698

CCCCCCCCCCCCCCCCCCNC(=O)OCC1(CO)CCCC1

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.50
ACHE P22303 4/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8304388 0.97 EPHX1 (0.50) EPHX1ACHE
SCHEMBL12039681 0.90 EPHX1 (0.51) EPHX1ACHE
SCHEMBL8303488 0.84 EPHX1 (0.49) EPHX1ACHE
SCHEMBL8304959 0.84 EPHX1 (0.49) EPHX1ACHE
SCHEMBL8887825 0.78 EPHX1 (0.47) EPHX1ACHE
SCHEMBL11081472 0.78 ACHE (0.47) ACHE
SCHEMBL9670749 0.78 EPHX1 (0.44) EPHX1ACHE
SCHEMBL10568241 0.77 EPHX1 (0.46) EPHX1ACHE
SCHEMBL10569695 0.77 EPHX1 (0.46) EPHX1ACHE
SCHEMBL10569694 0.77 EPHX1 (0.46) EPHX1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0607374-B1 NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS PO HANG IRON & STEEL (KR) 1999-04-07 EP disclosed
US-5700817-A Cyclic lipid derivatives as potent PAF antagonists POHANG IRON & STEEL CO., LTD. (KR) 1997-12-23 US disclosed
US-5610310-A Cyclic lipid derivatives as potent PAF antagonists POHANG IRON & STEEL CO., LTD (KR) 1997-03-11 US disclosed