Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.53 |
| ▸ | PLA2G2C | Q5R387 | 3/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.41 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.41 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7928161 | 0.93 | USP2 (0.52) | USP2HTTLPAR5PLA2G2CSPHK1 | |
| SCHEMBL13841203 | 0.93 | USP2 (0.52) | USP2HTTLPAR5PLA2G2CSPHK1 | |
| SCHEMBL13421955 | 0.93 | USP2 (0.52) | USP2HTTLPAR5PLA2G2CSPHK1 | |
| SCHEMBL11513826 | 0.87 | HSD17B10 (0.52) | USP2HTTLPAR5PLA2G2CSPHK1 | |
| SCHEMBL11649410 | 0.84 | USP2 (0.61) | USP2HTTLPAR5PLA2G2CSPHK1 | |
| SCHEMBL8527626 | 0.82 | USP2 (0.80) | USP2HTTLPAR5PLA2G2CSPHK1 | |
| SCHEMBL251104 | 0.82 | USP2 (0.80) | USP2HTTLPAR5PLA2G2CSPHK1 | |
| SCHEMBL10605202 | 0.82 | USP2 (0.80) | USP2HTTLPAR5PLA2G2CSPHK1 | |
| SCHEMBL10566561 | 0.82 | USP2 (0.80) | USP2HTTLPAR5PLA2G2CSPHK1 | |
| SCHEMBL9117095 | 0.82 | USP2 (0.80) | USP2HTTLPAR5PLA2G2CSPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607374-B1 | NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS | PO HANG IRON & STEEL (KR) | 1999-04-07 | — | — | EP | disclosed |
| US-5700817-A | Cyclic lipid derivatives as potent PAF antagonists | POHANG IRON & STEEL CO., LTD. (KR) | 1997-12-23 | — | — | US | disclosed |
| US-5610310-A | Cyclic lipid derivatives as potent PAF antagonists | POHANG IRON & STEEL CO., LTD (KR) | 1997-03-11 | — | — | US | disclosed |
| EP-0607374-A1 | NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS | POHANG IRON & STEEL CO., LTD. (KR) | 1994-07-27 | — | — | EP | disclosed |
| WO-1994000447-A1 | NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS | POHANG IRON & STEEL CO., LTD. (KR) | 1994-01-06 | — | — | WO | disclosed |