Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8280242 | 0.85 | ACE (0.49) | ACEF2PLGACE2CAPN1 | |
| SCHEMBL8303805 | 0.84 | F2 (0.45) | ACEF2PLGACE2CAPN1 | |
| SCHEMBL8302053 | 0.83 | ACE (0.43) | ACEF2PLGACE2CAPN1 | |
| SCHEMBL8302159 | 0.82 | ACE (0.46) | ACEF2PLGACE2CTRB1 | |
| SCHEMBL8299258 | 0.78 | ACE (0.52) | ACEF2ACE2 | |
| SCHEMBL14600191 | 0.77 | CMA1 (0.53) | ACEACE2TACR1CMA1 | |
| SCHEMBL8302113 | 0.76 | ACE (0.48) | ACEF2ACE2TACR1CTRB1 | |
| SCHEMBL13599070 | 0.75 | ELANE (0.56) | F2PLGCMA1 | |
| SCHEMBL11284841 | 0.74 | CMA1 (0.52) | ACEACE2CMA1 | |
| SCHEMBL11285943 | 0.74 | CMA1 (0.52) | ACEACE2CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106300-A1 | CAPTOPRIL DERIVATIVES | NICOX S.A. (FR) | 2004-12-09 | — | — | WO | disclosed |