Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.52 |
| ▸ | REN | P00797 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PEPD | P12955 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8300102 | 0.85 | ACE (0.46) | ACERENKDM4EF2LMNA | |
| SCHEMBL8301880 | 0.85 | ACE (0.46) | ACERENKDM4EF2LMNA | |
| SCHEMBL8301903 | 0.83 | ACE (0.35) | ACERENKDM4EF2LMNA | |
| SCHEMBL8302019 | 0.83 | FKBP1A (0.35) | ACERENKDM4EF2LMNA | |
| SCHEMBL5570416 | 0.83 | ACE (0.50) | ACERENKDM4EF2LMNA | |
| SCHEMBL8301957 | 0.82 | ACE (0.52) | ACERENKDM4EF2LMNA | |
| SCHEMBL11546811 | 0.80 | ACE (0.58) | ACERENKDM4EF2LMNA | |
| SCHEMBL8300072 | 0.80 | ACE (0.49) | ACERENKDM4EF2LMNA | |
| SCHEMBL5569964 | 0.79 | ACE (0.56) | ACERENKDM4EF2LMNA | |
| SCHEMBL8303943 | 0.78 | ACE (0.44) | ACEF2ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106300-A1 | CAPTOPRIL DERIVATIVES | NICOX S.A. (FR) | 2004-12-09 | — | — | WO | disclosed |