Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8303721 | 0.90 | KMT2A (0.50) | HTTKDM4EKMT2AMEN1HPGD | |
| SCHEMBL8311179 | 0.84 | KMT2A (0.47) | HTTKDM4EKMT2AMEN1USP2 | |
| SCHEMBL8305649 | 0.83 | HTT (0.61) | HTTKMT2AMEN1USP2TSHR | |
| SCHEMBL8308254 | 0.82 | KMT2A (0.58) | HTTKDM4EKMT2AMEN1HPGD | |
| SCHEMBL8311188 | 0.81 | KMT2A (0.74) | HTTKDM4EKMT2ATSHRALDH1A1 | |
| SCHEMBL8308076 | 0.81 | HPGD (0.55) | KMT2AMEN1HPGDUSP2TSHR | |
| SCHEMBL8305683 | 0.81 | RXFP1 (0.60) | HTTKDM4EKMT2AMEN1HPGD | |
| SCHEMBL8311182 | 0.81 | RXFP1 (0.61) | HTTKDM4EKMT2AMEN1HPGD | |
| SCHEMBL24532763 | 0.79 | USP2 (0.51) | HTTKDM4EKMT2AMEN1HPGD | |
| SCHEMBL8305644 | 0.79 | USP2 (0.50) | HTTKMT2AMEN1HPGDUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078731-A1 | QUINOLINE-CARBOXYLIC ACIDS AND THE DERIVATIVES THEREOF, A FOCUSED LIBRARY | 'CHEMICAL DIVERSITY RESEARCH INSTITUTE', LTD. (RU) | 2004-09-16 | — | — | WO | disclosed |