Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8308076 | 0.81 | HPGD (0.55) | USP2TSHRHPGDALDH1A1HSD17B10 | |
| SCHEMBL8303944 | 0.79 | HTT (0.59) | USP2TSHRHPGDALDH1A1HSD17B10 | |
| SCHEMBL8303721 | 0.78 | KMT2A (0.50) | USP2TSHRHPGDALDH1A1HSD17B10 | |
| SCHEMBL8305649 | 0.76 | HTT (0.61) | USP2TSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL8308254 | 0.74 | KMT2A (0.58) | USP2TSHRHPGDALDH1A1HSD17B10 | |
| SCHEMBL8311179 | 0.72 | KMT2A (0.47) | USP2TSHRALDH1A1HSD17B10KMT2A | |
| SCHEMBL8308077 | 0.71 | KMT2A (0.52) | USP2TSHRALDH1A1HSD17B10KMT2A | |
| SCHEMBL8308788 | 0.70 | USP2 (0.51) | USP2TSHRHPGDALDH1A1HSD17B10 | |
| SCHEMBL8311188 | 0.69 | KMT2A (0.74) | TSHRALDH1A1KMT2AMAPTHTT | |
| SCHEMBL8311182 | 0.68 | RXFP1 (0.61) | HPGDALDH1A1HSD17B10KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078731-A1 | QUINOLINE-CARBOXYLIC ACIDS AND THE DERIVATIVES THEREOF, A FOCUSED LIBRARY | 'CHEMICAL DIVERSITY RESEARCH INSTITUTE', LTD. (RU) | 2004-09-16 | — | — | WO | disclosed |