Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8304209 | 1.00 | PPARG (0.49) | PPARGFFAR1PPARAS1PR1CFTR | |
| SCHEMBL8307060 | 0.94 | PPARG (0.55) | PPARGFFAR1S1PR1CFTRBCL2 | |
| SCHEMBL8307062 | 0.94 | PPARG (0.55) | PPARGFFAR1S1PR1CFTRBCL2 | |
| SCHEMBL8309616 | 0.93 | PPARG (0.50) | PPARGFFAR1PPARAS1PR1CFTR | |
| SCHEMBL8309618 | 0.93 | PPARG (0.50) | PPARGFFAR1PPARAS1PR1CFTR | |
| SCHEMBL8444587 | 0.92 | PPARG (0.51) | PPARGFFAR1S1PR1BCL2HTT | |
| SCHEMBL8309782 | 0.92 | PPARG (0.51) | PPARGFFAR1PPARAS1PR1BCL2 | |
| SCHEMBL8309781 | 0.92 | PPARG (0.51) | PPARGFFAR1PPARAS1PR1BCL2 | |
| SCHEMBL8305089 | 0.90 | PPARG (0.51) | PPARGFFAR1S1PR1HTTMAPT | |
| SCHEMBL8305087 | 0.90 | PPARG (0.51) | PPARGFFAR1S1PR1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972959-A | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0708098-B1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1999-03-03 | — | — | EP | disclosed |
| EP-0708098-A1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1996-04-24 | — | — | EP | disclosed |