Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.46 |
| ▸ | RPS6KB1 | P23443 | 6/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 5/20 | 0.42 |
| ▸ | AURKA | O14965 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
| ▸ | AKT1 | P31749 | 3/20 | 0.41 |
| ▸ | INCENP | Q9NQS7 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F9 | P00740 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6332068 | 0.99 | F10 (0.46) | F10PRSS1RPS6KB1AURKBAURKA | |
| SCHEMBL6324252 | 0.89 | F10 (0.44) | F10PRSS1RPS6KB1AURKBAURKA | |
| Hydrochloric Acid SCHEMBL6332656 | 0.89 | F10 (0.38) | F10PRSS1RPS6KB1AURKBAURKA | |
| SCHEMBL3000659 | 0.87 | RPS6KB1 (0.42) | F10PRSS1RPS6KB1AURKBAURKA | |
| Hydrochloric Acid SCHEMBL6327132 | 0.86 | RPS6KB1 (0.42) | F10PRSS1RPS6KB1AURKBAURKA | |
| Hydrochloric Acid SCHEMBL6323304 | 0.86 | F10 (0.46) | F10PRSS1ITGB3ITGA2BF2 | |
| SCHEMBL6326837 | 0.85 | F10 (0.41) | F10PRSS1F2F9PLAU | |
| SCHEMBL3003536 | 0.80 | F10 (0.41) | F10PRSS1RPS6KB1AURKBAURKA | |
| SCHEMBL6329430 | 0.80 | F10 (0.43) | F10PRSS1RPS6KB1AURKAITGB3 | |
| Hydrochloric Acid SCHEMBL6324241 | 0.79 | F10 (0.42) | F10PRSS1RPS6KB1AURKAF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004080970-A1 | NOVEL BICYCLIC AROMATIC COMPOUNDS, THE PRODUCTION AND USE THEREOF IN THE FORM OF DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-09-23 | — | — | WO | disclosed |