Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 11/20 | 0.43 |
| ▸ | F2 | P00734 | 9/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.34 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6324241 | 0.99 | F10 (0.42) | F10PRSS1F2ROCK2AURKA | |
| SCHEMBL6324252 | 0.91 | F10 (0.44) | F10PRSS1F2AURKARPS6KB1 | |
| Hydrochloric Acid SCHEMBL6332656 | 0.89 | F10 (0.38) | F10PRSS1F2AURKARPS6KB1 | |
| SCHEMBL6330102 | 0.87 | CDK1 (0.40) | ROCK2 | |
| SCHEMBL8304367 | 0.80 | F10 (0.46) | F10PRSS1F2AURKARPS6KB1 | |
| SCHEMBL2998315 | 0.79 | F10 (0.40) | F10PRSS1F2AURKARPS6KB1 | |
| Hydrochloric Acid SCHEMBL6332068 | 0.79 | F10 (0.46) | F10PRSS1F2AURKARPS6KB1 | |
| SCHEMBL6325051 | 0.77 | CDK1 (0.45) | — | |
| SCHEMBL6326837 | 0.77 | F10 (0.41) | F10PRSS1F2 | |
| SCHEMBL8307162 | 0.73 | PDE5A (0.39) | F10PRSS1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050107409-A1 | Aromatic bicyclic compounds, preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-05-19 | — | — | US | disclosed |
| WO-2004080970-A1 | NOVEL BICYCLIC AROMATIC COMPOUNDS, THE PRODUCTION AND USE THEREOF IN THE FORM OF DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107409-A1 | Aromatic bicyclic compounds, preparation thereof and their use as pharmaceutical compositions | F12, F2, F11 | F10 11/4885PRSS1 182/4885F2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.