SCHEMBL8304445

SCHEMBL8304445

CCOC(=O)C(Cc1ccc(OCCN2CC(C)=C(CC)C2=O)cc1)OC

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 18/20 0.42
PPARG P37231 19/20 0.42
PPARD Q03181 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8306803 0.91 PPARG (0.52) PPARAPPARGPPARD
SCHEMBL8302577 0.90 PPARG (0.41) PPARAPPARGPPARD
SCHEMBL8307026 0.78 ITGB1 (0.41) PPARAPPARG
SCHEMBL14560652 0.77 PPARA (0.56) PPARAPPARGPPARD
SCHEMBL8301343 0.77 HRH3 (0.39) PPARG
SCHEMBL5380492 0.75 PPARA (0.54) PPARAPPARGPPARD
SCHEMBL5382747 0.75 PPARA (0.51) PPARAPPARGPPARD
SCHEMBL5578945 0.74 PPARA (0.56) PPARAPPARGPPARD
SCHEMBL5353565 0.74 PPARA (0.53) PPARAPPARGPPARD
SCHEMBL6574076 0.74 PPARA (0.53) PPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0903343-A1 Alpha-Substituted phenylpropionic acid derivative and medicine containing the same SSP Co., Ltd. (JP) 1999-03-24 EP disclosed