Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.68 |
| ▸ | MAPT | P10636 | 8/20 | 0.68 |
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | PKM | P14618 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | XBP1 | P17861 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27942800 | 0.93 | KMT2A (0.72) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL3645071 | 0.88 | MEN1 (0.62) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL25390636 | 0.87 | MEN1 (0.64) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL17512401 | 0.85 | ALDH1A1 (0.70) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL4250921 | 0.85 | MEN1 (0.58) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL10224200 | 0.84 | MEN1 (0.57) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL1663554 | 0.83 | PHGDH (0.59) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL6813218 | 0.83 | MEN1 (0.64) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL17512404 | 0.82 | POLB (0.70) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL3604124 | 0.81 | KMT2A (0.74) | MEN1KMT2AMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934068-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998009630-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-03-12 | — | — | WO | disclosed |