Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 7/20 | 0.41 |
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5419606 | 1.00 | MAPT (0.45) | MAPTSMN1; SMN2L3MBTL1ATMPPARA | |
| SCHEMBL5419610 | 1.00 | MAPT (0.45) | MAPTSMN1; SMN2L3MBTL1ATMPPARA | |
| SCHEMBL5610797 | 0.81 | LMNA (0.56) | MAPTSMN1; SMN2L3MBTL1PPARAPPARG | |
| SCHEMBL5610798 | 0.81 | LMNA (0.56) | MAPTSMN1; SMN2L3MBTL1PPARAPPARG | |
| SCHEMBL18193570 | 0.78 | ATM (0.57) | MAPTL3MBTL1ATMPPARAPPARG | |
| SCHEMBL18193569 | 0.78 | ATM (0.57) | MAPTL3MBTL1ATMPPARAPPARG | |
| SCHEMBL6268942 | 0.77 | SMN1; SMN2 (0.36) | MAPTSMN1; SMN2L3MBTL1ATMPPARA | |
| SCHEMBL6268940 | 0.77 | SMN1; SMN2 (0.36) | MAPTSMN1; SMN2L3MBTL1ATMPPARA | |
| SCHEMBL8686358 | 0.75 | MAPT (0.45) | MAPTSMN1; SMN2L3MBTL1ATMHPGD | |
| SCHEMBL6268881 | 0.75 | PPARG (0.39) | MAPTSMN1; SMN2L3MBTL1ATMPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972959-A | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0708098-B1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1999-03-03 | — | — | EP | disclosed |
| EP-0708098-A1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1996-04-24 | — | — | EP | disclosed |