Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.34 |
| ▸ | PPARA | Q07869 | 4/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8304714 | 1.00 | PPARG (0.34) | PPARGFFAR1PPARARARGRXRA | |
| SCHEMBL8307959 | 0.88 | PPARG (0.38) | PPARGFFAR1RARGRXRA | |
| SCHEMBL8307958 | 0.88 | PPARG (0.38) | PPARGFFAR1RARGRXRA | |
| SCHEMBL8305266 | 0.86 | PPARG (0.35) | PPARGFFAR1PPARARARGRXRA | |
| SCHEMBL8305268 | 0.86 | PPARG (0.35) | PPARGFFAR1PPARARARGRXRA | |
| SCHEMBL8306097 | 0.86 | PPARG (0.35) | PPARGFFAR1PPARARARGRXRA | |
| SCHEMBL8306092 | 0.86 | PPARG (0.35) | PPARGFFAR1PPARARARGRXRA | |
| SCHEMBL8308949 | 0.85 | PPARG (0.38) | PPARGFFAR1RARGRXRA | |
| SCHEMBL8308951 | 0.85 | PPARG (0.38) | PPARGFFAR1RARGRXRA | |
| SCHEMBL8307312 | 0.83 | PPARG (0.36) | PPARGFFAR1RARGRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972959-A | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0708098-B1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1999-03-03 | — | — | EP | disclosed |
| EP-0708098-A1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1996-04-24 | — | — | EP | disclosed |