Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.47 |
| ▸ | RXRA | P19793 | 2/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8387697 | 1.00 | PPARG (0.47) | PPARGRXRARARGNPC1KDM4E | |
| SCHEMBL8308499 | 0.86 | PPARG (0.45) | PPARGNPC1KDM4EMAPTKMT2A | |
| SCHEMBL8308501 | 0.86 | PPARG (0.45) | PPARGNPC1KDM4EMAPTKMT2A | |
| SCHEMBL8309782 | 0.84 | PPARG (0.51) | PPARGKDM4EMAPTKMT2AMEN1 | |
| SCHEMBL8309781 | 0.84 | PPARG (0.51) | PPARGKDM4EMAPTKMT2AMEN1 | |
| SCHEMBL8304309 | 0.84 | PPARG (0.52) | PPARGRXRARARGMEN1 | |
| SCHEMBL8304307 | 0.84 | PPARG (0.52) | PPARGRXRARARGMEN1 | |
| SCHEMBL8309649 | 0.83 | PPARG (0.48) | PPARGRXRARARGNPC1MAPT | |
| SCHEMBL8309646 | 0.83 | PPARG (0.48) | PPARGRXRARARGNPC1MAPT | |
| SCHEMBL8387956 | 0.83 | PPARG (0.62) | PPARGRXRARARGMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972959-A | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0708098-B1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1999-03-03 | — | — | EP | disclosed |
| EP-0708098-A1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1996-04-24 | — | — | EP | disclosed |