Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8308499 | 1.00 | PPARG (0.45) | PPARGL3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL8309646 | 0.90 | PPARG (0.48) | PPARGMEN1NPC1GAAMAPT | |
| SCHEMBL8309649 | 0.90 | PPARG (0.48) | PPARGMEN1NPC1GAAMAPT | |
| SCHEMBL8304791 | 0.86 | PPARG (0.47) | PPARGL3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL8387697 | 0.86 | PPARG (0.47) | PPARGL3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL8307062 | 0.86 | PPARG (0.55) | PPARGGAAMAPTHTT | |
| SCHEMBL8307060 | 0.86 | PPARG (0.55) | PPARGGAAMAPTHTT | |
| SCHEMBL8305087 | 0.86 | PPARG (0.51) | PPARGL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL8305089 | 0.86 | PPARG (0.51) | PPARGL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL8308451 | 0.84 | PPARG (0.49) | PPARGL3MBTL1NPC1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972959-A | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0708098-B1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1999-03-03 | — | — | EP | disclosed |
| EP-0708098-A1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1996-04-24 | — | — | EP | disclosed |